If given to patients with microbial diseases, microbial proliferation is usually enhanced and systemic dissemination is possible. These medications are all contraindicated in microbial diseases. Non-alcohol formulation – useful for alcoholics, patients with mucositis, xerostomia, ($18)ġ.Due to chemical deactivation, separate from toothpaste by 30 min.11.6% alcohol content will irritate ulcerations and enhance xerostomia, ($4-14).Sig: 10-15 ml mouth rinse 60-90 seconds and expectorate RX: Alcohol-Free Chlorhexidine 0.12% oral rinse (Paroex â ) Sig: 10 - 15 ml mouth rinse for 30 seconds and expectorateīID (after breakfast and HS), NPO 1\2 hr. RX: Chlorhexidine 0.12% oral rinse (Peridex â, g) FDA pregnancy category: X Even single doses in 1 st or 2 nd trimester can cause miscarriage.Serious interactions with statin drugs, psych drugs, sulfonylureas, warfarin, some antihypertensives and many other drug classes – always check for interactions before prescribing.Potent CYP2C9 inhibitor, moderate CYP3A4 inhibitor, causes QT prolongation.Price of 15 tablets is approximately $65 without insurance, cheaper to break 200 mg tablets in half.Loading dose results in steady state concentration in 2 days.Sig: Take 1 tablet BID for first day, then take 1 tablet daily for 10 – Better choice than Mycolog II which is >$100/15 g.Combination of ointment & cream is not ideal, but mupirocin cream may cost >$200/15 g while ointment is $20. ![]() Commercial 1% clotrimazole is only available in cream.
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